Pharmaceutical companies with single-use or stainless-steel bioreactors are trusting JM Canty’s visual analyzers for boosting production, efficiency, and quality control.
One of our New Jersey pharmaceutical customers have chosen the Canty Biocam, specifically for foam control, for its reduction of anti-foam usage and allowing for more product per batch.
A fermentation user reported up to a 30% drop in anti-foam usage per batch, and another reported the ability to roughly increase batch size by over 25%.
Bristol Myers Squibb conducted its own testing of the Canty analyzer for cell viability and found that CantyPharmaflow Imaging analyzer demonstrated the ability to measure early and late apoptosis, correlating to biomarkers such as Caspase and Nexin.
How can the Canty cameras help your fermenters and bioreactors? Ask one of our engineers!
Check out how JM Cantys foam detection works in this short video!
This past year has seen massive investments in vaccine research and development as well as production efficiency. The pharmaceutical and biotech market utilizes either stainless steel tanks or single-use tanks in one of the main chemical processes for this development – fermentation. During the fermentation growing process with bioreactor vessels, mass spectrometry analyzers have traditionally been used to measure exhausted gases from the process. Analysis of these gases can determine respiration metrics – specifically looking at concentrations of oxygen, carbon dioxide, nitrogen and argon in the sample stream. These values are then used to determine the oxygen uptakes rate (OUR) and carbon dioxide evaluation rate (CER).
In 2019, Schneider Electric’s AIT gas analyzer division released a new mass spectrometer for this very application – the MGA 1200CSseries. The MGA 1200CS was voted 2019 Product of the Year by the ISA Analyzer Division due to it drastically enhancing the respiration analysis by coming out with a mass spectrometer that has a 3 second response time: 1 second for purge, 1 second for measurement, 1 second for changeover to the next sample stream. With a vastly quickened response time, fermentation control can now be quickly adjusted and automated based upon the mass spectrometers readings allowing pharmaceutical research, development, and production to make a drastic jump forward technologically.
One of the world’s leading vaccine manufacturers has been successfully testing the system for the past year. By utilizing a full multi-stream sampling system and mass spectrometer deployment in labs with multiple bio-reactors. The system can do up to 100 sample streams with the appropriate sampling system.
The Schneider Electric MGA is ready for world deployment for any pharmaceutical or biotech applications where fermentation or bioreactors need quicker speeds!
Pictured is the startup at one of these facilities!
The Polytron 8900 UGLD contains an ultrasonic sensor that detects gas leaks regardless of environmental influences, even before a gas detection sensor detects a critical concentration.
The Polytron 8900 UGLD improves safety and efficiency and has a flexible installation with intrinsically safe remote sensor casing with cable also available. The sensor lifespan is 10+ years, which means no sensor replacement in the meantime. The results are easy to interpret as they are shown in percentages and the durable design and fully sealed sensor for reliable use even in harsh conditions.
An HSE study came to the conclusion that 36% of major gas releases and 69% of significant gas releases (0.1 – 1.0 kg/s) are undetected by gas detectors.
“Field trials have indicated that gas plumes in well ventilated areas may not be detected by fixed point or open path detectors. Analysis of hydrocarbon release incidents shows that conventional gas detectors have 65% detection efficiency.”
In the event of a potentially hazardous situation, the measured sound pressure is displayed in an easy-to-understand test value range of 0 to 100% (equivalent to 55 – 110 dBA). This value is easy to interpret, giving you complete transparency over the task at hand.
The Polytron 8900 UGLD triggers the gas leak alarm whenever the ultrasound caused by the gas leak exceeds background noise by 11% for a pre-adjustable period of up to 30 seconds.
This unique sensor is PVC coated ceramic piezo, which does not need weather guard. The sensor has a built-in self-test, which runs hourly. A co-centric ring design inner ring reverses polarity to become speaker. The sensor has calibration memory, built-in temperature sensor, and an intrinsically safe design that is field replaceable without declassifying area.
Models and Accessories
Polytron 8900 UGLD (Ultrasonic Gas Leak Detector) and Polytron 8900 UGLD (Ultrasonic Gas Leak Detector with Remote Sensor)
Calibration Kit – for regular functionality checks
Field Survey Device – pre-installation background noise analysis
Commissioning Test Device – enables you to create leak simulations of up to 100 g/sec
Draeger Polysoft Software – facilitates configuration and readout of the Polytron 8900 UGLD
For more information on the Polytron 8900 UGLD, contact us at sales@nealsystems.com!
Need a flowmeter using differential pressure and an orifice plate, but don’t find it easy doing all of the necessary calculations and parts assembly? Earlier this year we released our “OPA” product line, which featured a Foxboro IDP50S DP transmitter, a Lambda Square Orifice plate, and all of the necessary engineering know-how and parts to provide a total solution. One recent customer just placed their second order, since they valued the fact that we could provide them all of the necessary process details and engineering for one turn-key solution.
In case you missed it, here’s the video from our Technical Lead John Lamp, explaining the OPA series. In addition, Foxboro just released a new video on the transmitter we chose! Here is their latest video showing why this Pressure Transmitter Series from Schneider Electric is the most unique on the market!
The Draeger Flame 5000 detects characteristic properties of flames on the basis of a live video signal. By using Draeger’s sophisticated digital signal processing and software algorithmics – false alarms can practically be excluded and true flame emergencies can be detected from a safe distance.
The Flame 5000 is easy to install using a mounting bracket of stainless steel. The swiveling mount allows for the device to always be aimed towards a potential source of fire. Detection of fires of 0.1 m2 at a distance of 44m within a horizontal visual field as of 90 degrees. The detector’s field of view is a rectangular pyramid shape and represents a radial projection of the sensing element, therefore giving it the greatest coverage area of any flame detector currently available.
The detector transmits live video signals, which can also transmit alarm and status signals to a controller and fire alarm system. A 0 to 20 mA signal or relay outputs are available for this purpose. Additionally, video recordings of the time period immediately before and after a detected fire can be saved, collected and retrieved by means of a digital memory card.
The Flame 5000’s visual technology allows for instant verification of a fire alarm without the operator having to enter a dangerous area. The device status is displayed by tricolor LED light at the front of the device so that the status of the device is always clearly visible for persons working close to it. Green means normal operating conditions, the yellow LED indicates a fault and the red LED turns on if flames are detected.
The device is available with aluminum or stainless-steel housing and can be employed worldwide due to its variety of approvals: ATEX, IECEx, FM and cFM.
The Neal Systems service team can install and service all aspects of this device, as well as provide you the best complete solution for flame detection.
For more information on how the Draeger Flame 5000 can increase your safety and efficiency, contact us here!
